DISTRICT AND SUB-DISTRICT ANALYSIS OF CRYPTOCOCCAL ANTIGENAEMIA PREVALENCE AND SPECIMEN POSITIVITY IN KWAZULU-NATAL, SOUTH AFRICA

District and sub-district analysis of cryptococcal antigenaemia prevalence and specimen positivity in KwaZulu-Natal, South Africa

Background: Cryptococcal meningitis (CM) is a leading cause of mortality among HIV-positive South Africans.Reflex cryptococcal antigen (CrAg) testing of remnant plasma was offered as a pilot prior to implementation in October 2016 in KwaZulu-Natal province.The national reflex CrAg positivity was 5.4% compared to 7.3% for KwaZulu-Natal.Objectives: T

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The BAF complex in development and disease

Abstract The ATP-dependent chromatin remodelling complex BAF (= mammalian SWI/SNF complex) is crucial for the regulation of gene expression and differentiation.In the course of evolution from yeast to mammals, the BAF complex evolved an Gift Cards immense complexity with a high number of subunits encoded by gene families.In this way, tissue-specifi

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